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    Oxford Instruments algorithms imagej nih
    Algorithms Imagej Nih, supplied by Oxford Instruments, used in various techniques. Bioz Stars score: 99/100, based on 44287 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/algorithms+imagej+nih/Imaris/pm41824461-294-101-105
    Average 99 stars, based on 44287 article reviews
    algorithms imagej nih - by Bioz Stars, 2026-10
    99/100 stars

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    Article Title: Mitotic ER-mitochondria contact enhances mitochondrial Ca 2+ influx to promote cell division.
    Article Snippet: HCT116, HEK-293T and HeLa cells were purchased from ATCC.

    Article Title: Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER siRAD21 SMARTpool: ON-TARGET plus -J-006832-06: GCUCAGCCUUUGUGGAAUAJ-006832-07: GGGAGUAGUUCGAAUCUAUJ-006832-08: GACCAAGGUUCCAUAUUAUJ-006832-09: GCAUUGGAGCCUAUUGAUA Dharmacon L-006832-00-0010 siWAPL: GAGAGAUGUUUACGAGUUU Dharmacon J-026287-10 Primers for cloning This paper Table S1 Recombinant DNA pSPgRNA Perez-Pinera et al.74 Addgene plasmid # 47108 pCS446_pSPgSMC3 This study N/A 3xHA-TurboID-NLS_pCDNA3 Branon et al.49 Addgene plasmid #107171 pCRISPaint-mNeon Schmid-Burgk et al.75 Addgene plasmid #174092 pCS452_pCRISPaint-TurboID-pPGK-Hygro This study N/A pCAS9-mCherry-Frame+2 Schmid-Burgk et al.75 Addgene plasmid #66941 pX330 Chien et al.76 Addgene plasmid #158973 pLV-H2B-Neon-ires-Puro Drost et al.77 pLenti6-CENP-A-mCherry Pemble et al.78 Addgene plasmid #89767 Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/ Prism 9 GraphPad https://www.graphpad.com/scientific- software/prism/ Imaris Software (v9.7.2) Bitplane https://imaris.oxinst.com/ Trimmomatic v0.36 Bolger et al.79 http://www.usadellab.org/cms/index.php? page=trimmomatic BWA mem v0.7.16 Heng Li https://github.com/lh3/bwa?tab=readme- ov-file deepTools bamCoverage v3.5 deepTools https://deeptools.readthedocs.io/en/ develop/ LAMMPS Plimpton80 https://github.com/lammps/lammps Huygens Professional (v20.10) Scientific Volume Imaging https://svi.nl/Huygens-Professional capC-MAP software Buckle81 https://github.com/cbrackley/capC-MAP ll OPEN ACCESSArticle


    Software:

    Article Title: In toto imaging shows intravascular proliferation promotes transmigration of daughter cells during brain invasion of Cryptococcus neoformans.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/ IMARIS version 9.8 Bitplane, Oxford Instruments. https://imaris.oxinst.com/ HTSeq version 0.11.2 Open source https://htseq.readthedocs.io/; RRID: SCR_005514 DESeq2 version 1.38.0 Open source https://bioconductor.org/packages/release/ bioc/html/DESeq2.html; RRID: SCR_015687 Fastp (v0.20.1) Open source https://github.com/OpenGene/fastp; RRID: SCR_016962 GraphPad version 10 GraphPad Software https://www.graphpad.com Cell Reports 44, 116658, December 23, 2025 19 cassette was introduced into relevant recipient strains by the TRACE method as described above. ..

    Article Title: MSH6 regulates cGAS activity in antiviral and antitumor signaling pathways by governing its cytosolic/nuclear distribution.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Sting knockout B16-F10 This paper N/A cGas/Msh6 knockout B16-F10 This paper N/A Experimental models: Organisms/strains C57BL/6J mice (wild-type) SPF (Beijing) Biotechnology Co., Ltd RRID: MGI:3028467 Oligonucleotides ISD:sense 5 ′ -TACAGATCTACTAGTGATC TATGACTGATCTGTACATGATCTACA-3 ′ This paper N/A primers for RT-qPCR, see Table S2 This paper N/A sgRNA and shRNA, see Table S3 This paper N/A Recombinant DNA ISRE-Luc Hongbing Shu, Wuhan University N/A IFNβ-Luc Hongbing Shu, Wuhan University N/A NF-κB-Luc Zhijian Chen, University of Texas, Southwestern Medical Center at Dallas N/A Other recombinant DNA used in this study are listed in Table S1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/download.html Imaris 9.5.1 IMARIS https://imaris.oxinst.com/ NIS-Elements AR Analysis 5.20.00 NIKON https://www.microscope.healthcare.nikon. com/products/software/nis-elements GraphPad Prism 8 GraphPad https://www.graphpad.com/guides/prism/ 8/user-guide/tips_for_using_prism.htm Flowjo BD Biosciences https://www.flowjo.com/flowjo/download Cell Reports 45, 117059, March 24, 2026 19 ..

    Article Title: The correct connectivity of the DG-CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Anti-bassoon mouse monoclonal antibody Enzo Life Sciences Ref ADI-VAM-PS003 Anti-DCX guinea pig polyclonal antibody Millipore Ref AB2253 Living Colors® DsRed polyclonal antibody Takara/Clontech Ref 632496 Anti-GAPDH mouse monoclonal antibody Millipore Ref MAB374 Anti-GFP chicken polyclonal antibody Abcam Ref Ab13970 Anti-GPC4 rabbit polyclonal antibody Proteintech Ref 13048-1-AP Anti-GPR158 rabbit polyclonal antibody Sigma Ref SAB4502509 Anti-HA.11 mouse monoclonal antibody Biolegend Ref 901513 Anti-myc (clone 9E10) mouse monoclonal antibody Biolegend Ref 626802 Anti-PSD95 mouse monoclonal antibody Thermoscientific Ref MA1-045 Anti-Synaptotagmin7 mouse monoclonal antibody Millipore Ref MABN655 Anti-VGLUT3 mouse monoclonal antibody SySy Ref 135 211 Anti-Synaptoporin rabbit polyclonal antibody SySy Ref 102 002 Anti-synapsin1 rabbit polyclonal antibody SySy Ref 106 002 Anti-Tau (clone PC1C6) mouse monoclonal antibody Millipore Ref MAB3420 Anti-Vangl2 rabbit polyclonal antibody Montcouquiol et al., 2006 Ref 456 Anti-Znt3 mouse monoclonal antibody SySy Ref 197011 Anti-Rabbit Alexa 546 goat secondary antibody Invitrogen Ref A11035 Anti-Rabbit Alexa 488 goat secondary antibody Jackson Laboratory Ref 111-545-144 Anti-Mouse Alexa 594 goat secondary antibody Jackson Laboratory Ref 115-585-166 Anti-Guinea pig Alexa 488 goat secondary antibody Invitrogen Ref A11073 Anti-Chicken Alexa 488 goat secondary antibody Jackson Laboratory Ref 103-545-155 Anti-Rabbit HRP goat secondary antibody Jackson Laboratory Ref 111-035-144 Anti-Mouse HRP goat secondary antibody Jackson Laboratory Ref 115-035-146 Anti-Rabbit HRP mouse secondary antibody Jackson Laboratory Ref 211-032-171 In-situ hybridization probe RNAscope Probe-Mm-Vangl2 Advanced Cell Diagnostics Ref316781 Bacterial and virus strains AAV2/9-CaMKII(0.4)-mCherry- Vector Biolabs Service request [1. .. 9x1012 gcp/ml] AAV2/9-CaMKII(0.4)-mCherry-2A-mVANGL2 -WPRE Vector Biolabs Service request [5.9x1013 gcp/ml or 1.7x1013 gcp/ml] Experimental models: Organisms/strains Vangl2flox mice Prof. D. Henderson, UK Ramsbottom et al., 2014 Plos Genetics Emx1B6.129S2-Emx1tm1(cre)Krj/J (Emx1-Cre) mice Jackson Laboratory RRID:IMSR_JAX:005 628 Jo ur n l P re -p ro of Recombinant DNA GFP-Vangl2 Montcouquiol et al., 2006 HA-GPR158 Condomitti et al., 2018 HA-GPC4 Condomitti et al., 2018 GPC4-myc Origene Ref MR208834 Software and algorithms ImageJ NIH https://imagej.nih.gov/i j/; RRID: SCR_003070 Imaris BITPLANE http://www.bitplane.co m/imaris; RRID: SCR_007370 Microscope Image Browser (MIB) University of Helsinki http://mib.helsinki.fi/in dex.html Digital Micrograph Software Gatan http://www.gatan.com/ products/tem-analysis/ gatan-microscopysuite-software ZEN digital imaging for light microscopy Zeiss https://www.zeiss.com /microscopy/int/produc ts/ microscopesoftware/zen.html; RRID: SCR_013672 GraphPad Prism8 GraphPad Software https://www.graphpad. com/scientificsoftware/ prism/; RRID: SCR_002798 LasX Leica https://www.leicamicr osystems. com Ethovision XT 13 Noldus http://www.noldus.co m Neuromatic WaveMetrics Igor Pro 6.0 environment Image Lab software Viewpoint behavior Technology http://www.viewpoint. fr/en/home Other Digital Stereotaxic Frame, 18° Ear Bars WPI Ref 502300 Mouse/Neonatal Rat Adapter WPI Ref 502063 UMP III (one) & Micro4 Controller WPI Ref UMP3-1 Elevated 8-arm maze with automatized platform IMETRONIC https://www.imetronic. com/appareils/ Jo ur na l P re -p ro of ..

    Article Title: Mitotic ER-mitochondria contact enhances mitochondrial Ca 2+ influx to promote cell division.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER BSA Servicebio G5001 STLC Sigma-Aldrich SPE006 MG132 Sigma-Aldrich M8699 Bleomycin sulfate MedChemExpress HY-17565 Protease Inhibitor Cocktail MedChemExpress HY-K0010 Thymidine Sigma-Aldrich V900391 Enhanced chemiluminescence Sigma-Aldrich WBKLS0500 ATP MedChemExpress HY-B0345A DTT Sigma-Aldich D0632 Histamine 3A Chemicals A02646 Triton X-100 Sigma-Aldrich T9284 CGP37157 MedChemExpress HY-15754 EMbed 812 resin Electron Microscopy Sciences #14120 1.4-nm gold-conjugated Fab’ fragment Nanoprobes #2004 Critical commercial assays FastStart Essential DNA Green Master Roche 06402712001 Duolink PLA assay kit Sigma-Aldrich DUO92008 JC-1 assay kit MedChemExpress HY-K0601 Seahorse XF Cell Mito Stress Test Kit Agilent 103015–100 GoldEnhance EM Plus kit Nanoprobes #2114 Deposited data mass spectrometry data of MAM This paper IProX: IPX0006293000 mass spectrometry data of GFP-LBR coIP This paper IProX: IPX0006297000 Experimental models: Cell lines HEK293T cell ATCC CRL-11268 HeLa cell ATCC CCL-2 HCT116 cell ATCC CCL-247 LBR KO HeLa cell This paper N/A EMD KO HeLa cell This paper N/A Oligonucleotides LBR KO sgRNA1: 50- TGACCTTGATCGACTCCCT-30 This paper N/A LBR KO sgRNA2: 50- TTCCCCTTCCAGACGCCGA-30 This paper N/A EMD KO sgRNA: 50- GCGCAGCAAGG TGGTCAGCT-30 This paper N/A Recombinant DNA Plasmid: 4mt-GCaMP6 Gift from Dr. D. De Stefani, University of Padua, Italy N/A Plasmid: mito-R-GECO1.2 Gift from Drs. Jianguo Chen and Junlin Teng, Peking University, China N/A Plasmid: pEGFP-N1-LBR This paper N/A Plasmid: pEGFP-C2-Sec61b This paper N/A Plasmid: pEGFP-N1-LBR211–615 This paper N/A Plasmid: pEGFP-N1-LBR1–585 This paper N/A Plasmid: pEGFP-N1-LBRD211–585 This paper N/A Plasmid: pEGFP-N1-LBR1–210 This paper N/A Plasmid: pEGFP-N1-LBR211–585 This paper N/A (Continued on next page) Cell Reports 43, 114794, October 22, 2024 17 .. REAGENT or RESOURCE SOURCE IDENTIFIER Plasmid: pEGFP-N1-LBR5A This paper N/A Plasmid: pEGFP-N1-LBR5D This paper N/A Plasmid: pcDNA3.1-flag- AKAP1-BFPUBC6 This paper N/A Plasmid: pcDNA3.1-mCherry-COX8 This paper N/A Plasmid: RFP-H2B Our Laboratory N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/ Volocity v.6.1.1 PerkinElmer N/A Imaris v.9.3.1 Bitplane https://imaris.oxinst.com/versions/9-3 Amira 2019.2.0 Thermo Scientific https://www.thermofisher.cn/cn/zh/home/ global/forms/industrial/amira-softwaretrial. html GraphPad Prism v.8.2.1 GraphPad https://www.graphpad.com/ Seahorse Analytics Agilent https://www.agilent.com.cn/zh-cn/ product/cell-analysis/real-time-cellmetabolic-analysis/xf-software/agilentseahorse-analytics-787485 LightCycler Software Version1.1.0 Roche N/A .. HCT116, HEK-293T and HeLa cells were purchased from ATCC.

    Article Title: ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER NuPAGE TM LDS Sample Buffer (4X) Thermo Fisher Scientific Cat# NP0008 DTT Sigma Cat# D9779 Dynabeads Protein A Thermo Fisher Scientific Cat# 10008D Dynabeads Protein G Thermo Fisher Scientific Cat# 10009D NP-40 Sigma Cat# I8896 Tris-HCl (1M, pH 8.0) Thermo Fisher Scientific Cat# AM9856 Tris-HCl (1M, pH 7.0) Thermo Fisher Scientific Cat# AM9850 Glycerol Sigma Cat# G5516 Protease inhibitor (cOmplete EDTA-free) Roche Cat# 11873580001 Tween 20 Fisher Cat# BP337-500 Pierce Universal Nuclease Thermo Fisher Scientific Cat# 88701 Glucose Sigma Cat# G7021 Oligomycin-A Sigma Cat# 75351 2DG AlfaAesar Cat# AAL0733806 FCCP Sigma Cat# C2920 Rotenone Sigma Cat# 557368 1M MgCl 2 Thermo Fisher Scientific Cat# AM9530G 0.5M EDTA (pH 8.0) Sigma Cat# 324506 Sodium deoxycholate Sigma Cat# D6750 SDS Sigma Cat# L3771 RNasin® Plus Promega Cat# N2615 GlycoBlue TM Thermo Fisher Scientific Cat# AM9516 ERCC RNA Spike-In Mix Thermo Fisher Scientific Cat# 4456740 Critical commercial assays NEBNext® Ultra TM II Directional RNA Library Prep Kit for Illumina® NEB Cat# E7765 RiboMinus TM Eukaryote Kit for RNA-seq Thermo Fisher Scientific Cat# A1083708 Direct-zol RNA Miniprep kit Zymo Research Cat# R2052 Deposited data Raw and analyzed sequencing data This paper GSE293278 Proteomics data This paper PXD069896 Experimental models: Cell lines WT-HEK-293T Chung et al. 14 N/A ADAR1 KO-HEK-293T Chung et al. 14 N/A WT-HUES8 Chung et al. 14 N/A ADAR1 KO-HUES8 Chung et al. 14 N/A WT-HeLa Pfaller et al. 16 N/A ADAR1p150KO-HeLa Pfaller et al. 16 N/A ADAR1 KO-HeLa Pfaller et al. 16 N/A WT-HAP1 This paper N/A E912A KI-HAP1 This paper N/A ADAR1 KO-HAP1 This paper N/A Human Dermal Fibroblasts ATCC Cat# PCS-201-012 Oligonucleotides Primers for qRT-PCR, see Table S9 This paper N/A gRNA_ADAR1 KO_clone #1_1: CATGAGATGTGACTGCACAG This paper N/A (Continued on next page) Cell Reports 45, 117026, March 24, 2026 23 .. REAGENT or RESOURCE SOURCE IDENTIFIER gRNA_ADAR1 KO_clone #1_2: GGAATCCATGATGCCCAACA This paper N/A gRNA_ADAR1 KO_clone #2_1: TTCTTGTAGGGTGAACACCG This paper N/A gRNA_ADAR1 KO_clone #2_2: TGATTGGTTTTGGCCGTACG This paper N/A gRNA_E912A KI: GCCATGCAGAAATAATCTCC This paper N/A Donor template_E912A KI_clone #1: AAGGAGATTCTCTCAGCCTAAA AGGAGAAACTGTCAATGACTGCCA TGCAGCCATAATCTCCCGGAGAGGC TTCATCAGGTGAGCGAGGTCAGAGCTG TGGCCCGGCTGCCCGG This paper N/A Donor template_E912A KI_clone #2: TCTCAGCCTAAAAGGAGAAACTGTCAA TGACTGCCATGCAGCCATAATC TCCAGAAGAGGCTTCATCAGG TGAGCGAGGTCAGAGCTGTGG CCCGGCTGCCCGG This paper N/A ON-TARGETplus TM siRNA targeting ADAR1 Dharmacon Cat# L-008630-00-0005 ON-TARGETplus TM siRNA targeting PNPT1 Dharmacon Cat# L-019454-01-0005 ON-TARGETplus TM siRNA targeting SUV3 Dharmacon Cat# L-017841-01-0005 Recombinant DNA pSpCas9(BB)-2A-GFP (PX458) Ran et al. 95 Addgene plasmid Cat# 48138 pcDNA TM 3.1 Thermo Fisher Scientific Cat# V79020 ADAR1p110_pcDNA TM 3.1 This paper N/A ADAR1p150_pcDNA TM 3.1 This paper N/A p150_EAA_pcDNA TM 3.1 This paper N/A p150_E912A_pcDNA TM 3.1 This paper N/A p150_EAA/E912A_pcDNA TM 3.1 This paper N/A hPTGS2_pcDNA3.1 Chen et al. 96 Addgene plasmid Cat# 102498 ISG15_pcDNA TM 3.1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij Imaris Oxford Instruments https://imaris.oxinst.com Prism 10.0 GraphPad Software https://www.graphpad.com/features DIA-NN APTILA https://aptila.bio NormalizerDE Willforss et al. 97 https://normalyzerde.immunoprot.lth.se FastQC v0.11.5 Andrews et al. 98 http://www.bioinformatics.babraham.ac. uk/projects/fastqc Fastp v0.20.1 Chen et al. 99 https://github.com/OpenGene/fastp STAR v2.7.3a and v2.7.9a Dobin et al. 100 https://github.com/alexdobin/STAR featureCounts v1.6.4 Liao et al. 101 https://subread.sourceforge.net/ featureCounts.html DESeq2 Love et al. 67 https://github.com/thelovelab/DESeq2 RepeatMasker Smit et al. 102 https://www.repeatmasker.org BEDTools v2.30.0 Quinlan et al. 103 https://bedtools.readthedocs.io/en/latest Cutadapt v4.9 Martin et al. 104 https://cutadapt.readthedocs.io/en/stable SEISMIC-RNA v2.7.9a Allan et al. 52 https://github.com/rouskinlab/seismic-rna BWA 0.7.18-r1243-dirty Li et al. 105 https://github.com/lh3/bwa DaPars v2.1 Li et al. 56 https://github.com/3UTR/DaPars2 24 Cell Reports 45, 117026, March 24, 2026 ..

    Knock-Out:

    Article Title: MSH6 regulates cGAS activity in antiviral and antitumor signaling pathways by governing its cytosolic/nuclear distribution.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Sting knockout B16-F10 This paper N/A cGas/Msh6 knockout B16-F10 This paper N/A Experimental models: Organisms/strains C57BL/6J mice (wild-type) SPF (Beijing) Biotechnology Co., Ltd RRID: MGI:3028467 Oligonucleotides ISD:sense 5 ′ -TACAGATCTACTAGTGATC TATGACTGATCTGTACATGATCTACA-3 ′ This paper N/A primers for RT-qPCR, see Table S2 This paper N/A sgRNA and shRNA, see Table S3 This paper N/A Recombinant DNA ISRE-Luc Hongbing Shu, Wuhan University N/A IFNβ-Luc Hongbing Shu, Wuhan University N/A NF-κB-Luc Zhijian Chen, University of Texas, Southwestern Medical Center at Dallas N/A Other recombinant DNA used in this study are listed in Table S1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/download.html Imaris 9.5.1 IMARIS https://imaris.oxinst.com/ NIS-Elements AR Analysis 5.20.00 NIKON https://www.microscope.healthcare.nikon. com/products/software/nis-elements GraphPad Prism 8 GraphPad https://www.graphpad.com/guides/prism/ 8/user-guide/tips_for_using_prism.htm Flowjo BD Biosciences https://www.flowjo.com/flowjo/download Cell Reports 45, 117059, March 24, 2026 19 ..

    shRNA:

    Article Title: MSH6 regulates cGAS activity in antiviral and antitumor signaling pathways by governing its cytosolic/nuclear distribution.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Sting knockout B16-F10 This paper N/A cGas/Msh6 knockout B16-F10 This paper N/A Experimental models: Organisms/strains C57BL/6J mice (wild-type) SPF (Beijing) Biotechnology Co., Ltd RRID: MGI:3028467 Oligonucleotides ISD:sense 5 ′ -TACAGATCTACTAGTGATC TATGACTGATCTGTACATGATCTACA-3 ′ This paper N/A primers for RT-qPCR, see Table S2 This paper N/A sgRNA and shRNA, see Table S3 This paper N/A Recombinant DNA ISRE-Luc Hongbing Shu, Wuhan University N/A IFNβ-Luc Hongbing Shu, Wuhan University N/A NF-κB-Luc Zhijian Chen, University of Texas, Southwestern Medical Center at Dallas N/A Other recombinant DNA used in this study are listed in Table S1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/download.html Imaris 9.5.1 IMARIS https://imaris.oxinst.com/ NIS-Elements AR Analysis 5.20.00 NIKON https://www.microscope.healthcare.nikon. com/products/software/nis-elements GraphPad Prism 8 GraphPad https://www.graphpad.com/guides/prism/ 8/user-guide/tips_for_using_prism.htm Flowjo BD Biosciences https://www.flowjo.com/flowjo/download Cell Reports 45, 117059, March 24, 2026 19 ..

    Recombinant:

    Article Title: MSH6 regulates cGAS activity in antiviral and antitumor signaling pathways by governing its cytosolic/nuclear distribution.
    Article Snippet: .. REAGENT or RESOURCE SOURCE IDENTIFIER Sting knockout B16-F10 This paper N/A cGas/Msh6 knockout B16-F10 This paper N/A Experimental models: Organisms/strains C57BL/6J mice (wild-type) SPF (Beijing) Biotechnology Co., Ltd RRID: MGI:3028467 Oligonucleotides ISD:sense 5 ′ -TACAGATCTACTAGTGATC TATGACTGATCTGTACATGATCTACA-3 ′ This paper N/A primers for RT-qPCR, see Table S2 This paper N/A sgRNA and shRNA, see Table S3 This paper N/A Recombinant DNA ISRE-Luc Hongbing Shu, Wuhan University N/A IFNβ-Luc Hongbing Shu, Wuhan University N/A NF-κB-Luc Zhijian Chen, University of Texas, Southwestern Medical Center at Dallas N/A Other recombinant DNA used in this study are listed in Table S1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/download.html Imaris 9.5.1 IMARIS https://imaris.oxinst.com/ NIS-Elements AR Analysis 5.20.00 NIKON https://www.microscope.healthcare.nikon. com/products/software/nis-elements GraphPad Prism 8 GraphPad https://www.graphpad.com/guides/prism/ 8/user-guide/tips_for_using_prism.htm Flowjo BD Biosciences https://www.flowjo.com/flowjo/download Cell Reports 45, 117059, March 24, 2026 19 ..

    Article Title: The correct connectivity of the DG-CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Anti-bassoon mouse monoclonal antibody Enzo Life Sciences Ref ADI-VAM-PS003 Anti-DCX guinea pig polyclonal antibody Millipore Ref AB2253 Living Colors® DsRed polyclonal antibody Takara/Clontech Ref 632496 Anti-GAPDH mouse monoclonal antibody Millipore Ref MAB374 Anti-GFP chicken polyclonal antibody Abcam Ref Ab13970 Anti-GPC4 rabbit polyclonal antibody Proteintech Ref 13048-1-AP Anti-GPR158 rabbit polyclonal antibody Sigma Ref SAB4502509 Anti-HA.11 mouse monoclonal antibody Biolegend Ref 901513 Anti-myc (clone 9E10) mouse monoclonal antibody Biolegend Ref 626802 Anti-PSD95 mouse monoclonal antibody Thermoscientific Ref MA1-045 Anti-Synaptotagmin7 mouse monoclonal antibody Millipore Ref MABN655 Anti-VGLUT3 mouse monoclonal antibody SySy Ref 135 211 Anti-Synaptoporin rabbit polyclonal antibody SySy Ref 102 002 Anti-synapsin1 rabbit polyclonal antibody SySy Ref 106 002 Anti-Tau (clone PC1C6) mouse monoclonal antibody Millipore Ref MAB3420 Anti-Vangl2 rabbit polyclonal antibody Montcouquiol et al., 2006 Ref 456 Anti-Znt3 mouse monoclonal antibody SySy Ref 197011 Anti-Rabbit Alexa 546 goat secondary antibody Invitrogen Ref A11035 Anti-Rabbit Alexa 488 goat secondary antibody Jackson Laboratory Ref 111-545-144 Anti-Mouse Alexa 594 goat secondary antibody Jackson Laboratory Ref 115-585-166 Anti-Guinea pig Alexa 488 goat secondary antibody Invitrogen Ref A11073 Anti-Chicken Alexa 488 goat secondary antibody Jackson Laboratory Ref 103-545-155 Anti-Rabbit HRP goat secondary antibody Jackson Laboratory Ref 111-035-144 Anti-Mouse HRP goat secondary antibody Jackson Laboratory Ref 115-035-146 Anti-Rabbit HRP mouse secondary antibody Jackson Laboratory Ref 211-032-171 In-situ hybridization probe RNAscope Probe-Mm-Vangl2 Advanced Cell Diagnostics Ref316781 Bacterial and virus strains AAV2/9-CaMKII(0.4)-mCherry- Vector Biolabs Service request [1. .. 9x1012 gcp/ml] AAV2/9-CaMKII(0.4)-mCherry-2A-mVANGL2 -WPRE Vector Biolabs Service request [5.9x1013 gcp/ml or 1.7x1013 gcp/ml] Experimental models: Organisms/strains Vangl2flox mice Prof. D. Henderson, UK Ramsbottom et al., 2014 Plos Genetics Emx1B6.129S2-Emx1tm1(cre)Krj/J (Emx1-Cre) mice Jackson Laboratory RRID:IMSR_JAX:005 628 Jo ur n l P re -p ro of Recombinant DNA GFP-Vangl2 Montcouquiol et al., 2006 HA-GPR158 Condomitti et al., 2018 HA-GPC4 Condomitti et al., 2018 GPC4-myc Origene Ref MR208834 Software and algorithms ImageJ NIH https://imagej.nih.gov/i j/; RRID: SCR_003070 Imaris BITPLANE http://www.bitplane.co m/imaris; RRID: SCR_007370 Microscope Image Browser (MIB) University of Helsinki http://mib.helsinki.fi/in dex.html Digital Micrograph Software Gatan http://www.gatan.com/ products/tem-analysis/ gatan-microscopysuite-software ZEN digital imaging for light microscopy Zeiss https://www.zeiss.com /microscopy/int/produc ts/ microscopesoftware/zen.html; RRID: SCR_013672 GraphPad Prism8 GraphPad Software https://www.graphpad. com/scientificsoftware/ prism/; RRID: SCR_002798 LasX Leica https://www.leicamicr osystems. com Ethovision XT 13 Noldus http://www.noldus.co m Neuromatic WaveMetrics Igor Pro 6.0 environment Image Lab software Viewpoint behavior Technology http://www.viewpoint. fr/en/home Other Digital Stereotaxic Frame, 18° Ear Bars WPI Ref 502300 Mouse/Neonatal Rat Adapter WPI Ref 502063 UMP III (one) & Micro4 Controller WPI Ref UMP3-1 Elevated 8-arm maze with automatized platform IMETRONIC https://www.imetronic. com/appareils/ Jo ur na l P re -p ro of ..

    Article Title: ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER NuPAGE TM LDS Sample Buffer (4X) Thermo Fisher Scientific Cat# NP0008 DTT Sigma Cat# D9779 Dynabeads Protein A Thermo Fisher Scientific Cat# 10008D Dynabeads Protein G Thermo Fisher Scientific Cat# 10009D NP-40 Sigma Cat# I8896 Tris-HCl (1M, pH 8.0) Thermo Fisher Scientific Cat# AM9856 Tris-HCl (1M, pH 7.0) Thermo Fisher Scientific Cat# AM9850 Glycerol Sigma Cat# G5516 Protease inhibitor (cOmplete EDTA-free) Roche Cat# 11873580001 Tween 20 Fisher Cat# BP337-500 Pierce Universal Nuclease Thermo Fisher Scientific Cat# 88701 Glucose Sigma Cat# G7021 Oligomycin-A Sigma Cat# 75351 2DG AlfaAesar Cat# AAL0733806 FCCP Sigma Cat# C2920 Rotenone Sigma Cat# 557368 1M MgCl 2 Thermo Fisher Scientific Cat# AM9530G 0.5M EDTA (pH 8.0) Sigma Cat# 324506 Sodium deoxycholate Sigma Cat# D6750 SDS Sigma Cat# L3771 RNasin® Plus Promega Cat# N2615 GlycoBlue TM Thermo Fisher Scientific Cat# AM9516 ERCC RNA Spike-In Mix Thermo Fisher Scientific Cat# 4456740 Critical commercial assays NEBNext® Ultra TM II Directional RNA Library Prep Kit for Illumina® NEB Cat# E7765 RiboMinus TM Eukaryote Kit for RNA-seq Thermo Fisher Scientific Cat# A1083708 Direct-zol RNA Miniprep kit Zymo Research Cat# R2052 Deposited data Raw and analyzed sequencing data This paper GSE293278 Proteomics data This paper PXD069896 Experimental models: Cell lines WT-HEK-293T Chung et al. 14 N/A ADAR1 KO-HEK-293T Chung et al. 14 N/A WT-HUES8 Chung et al. 14 N/A ADAR1 KO-HUES8 Chung et al. 14 N/A WT-HeLa Pfaller et al. 16 N/A ADAR1p150KO-HeLa Pfaller et al. 16 N/A ADAR1 KO-HeLa Pfaller et al. 16 N/A WT-HAP1 This paper N/A E912A KI-HAP1 This paper N/A ADAR1 KO-HAP1 This paper N/A Human Dermal Fibroblasts ATCC Cat# PCS-201-012 Oligonucleotides Primers for qRT-PCR, see Table S9 This paper N/A gRNA_ADAR1 KO_clone #1_1: CATGAGATGTGACTGCACAG This paper N/A (Continued on next page) Cell Reports 45, 117026, March 24, 2026 23 .. REAGENT or RESOURCE SOURCE IDENTIFIER gRNA_ADAR1 KO_clone #1_2: GGAATCCATGATGCCCAACA This paper N/A gRNA_ADAR1 KO_clone #2_1: TTCTTGTAGGGTGAACACCG This paper N/A gRNA_ADAR1 KO_clone #2_2: TGATTGGTTTTGGCCGTACG This paper N/A gRNA_E912A KI: GCCATGCAGAAATAATCTCC This paper N/A Donor template_E912A KI_clone #1: AAGGAGATTCTCTCAGCCTAAA AGGAGAAACTGTCAATGACTGCCA TGCAGCCATAATCTCCCGGAGAGGC TTCATCAGGTGAGCGAGGTCAGAGCTG TGGCCCGGCTGCCCGG This paper N/A Donor template_E912A KI_clone #2: TCTCAGCCTAAAAGGAGAAACTGTCAA TGACTGCCATGCAGCCATAATC TCCAGAAGAGGCTTCATCAGG TGAGCGAGGTCAGAGCTGTGG CCCGGCTGCCCGG This paper N/A ON-TARGETplus TM siRNA targeting ADAR1 Dharmacon Cat# L-008630-00-0005 ON-TARGETplus TM siRNA targeting PNPT1 Dharmacon Cat# L-019454-01-0005 ON-TARGETplus TM siRNA targeting SUV3 Dharmacon Cat# L-017841-01-0005 Recombinant DNA pSpCas9(BB)-2A-GFP (PX458) Ran et al. 95 Addgene plasmid Cat# 48138 pcDNA TM 3.1 Thermo Fisher Scientific Cat# V79020 ADAR1p110_pcDNA TM 3.1 This paper N/A ADAR1p150_pcDNA TM 3.1 This paper N/A p150_EAA_pcDNA TM 3.1 This paper N/A p150_E912A_pcDNA TM 3.1 This paper N/A p150_EAA/E912A_pcDNA TM 3.1 This paper N/A hPTGS2_pcDNA3.1 Chen et al. 96 Addgene plasmid Cat# 102498 ISG15_pcDNA TM 3.1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij Imaris Oxford Instruments https://imaris.oxinst.com Prism 10.0 GraphPad Software https://www.graphpad.com/features DIA-NN APTILA https://aptila.bio NormalizerDE Willforss et al. 97 https://normalyzerde.immunoprot.lth.se FastQC v0.11.5 Andrews et al. 98 http://www.bioinformatics.babraham.ac. uk/projects/fastqc Fastp v0.20.1 Chen et al. 99 https://github.com/OpenGene/fastp STAR v2.7.3a and v2.7.9a Dobin et al. 100 https://github.com/alexdobin/STAR featureCounts v1.6.4 Liao et al. 101 https://subread.sourceforge.net/ featureCounts.html DESeq2 Love et al. 67 https://github.com/thelovelab/DESeq2 RepeatMasker Smit et al. 102 https://www.repeatmasker.org BEDTools v2.30.0 Quinlan et al. 103 https://bedtools.readthedocs.io/en/latest Cutadapt v4.9 Martin et al. 104 https://cutadapt.readthedocs.io/en/stable SEISMIC-RNA v2.7.9a Allan et al. 52 https://github.com/rouskinlab/seismic-rna BWA 0.7.18-r1243-dirty Li et al. 105 https://github.com/lh3/bwa DaPars v2.1 Li et al. 56 https://github.com/3UTR/DaPars2 24 Cell Reports 45, 117026, March 24, 2026 ..

    Microscopy:

    Article Title: The correct connectivity of the DG-CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Anti-bassoon mouse monoclonal antibody Enzo Life Sciences Ref ADI-VAM-PS003 Anti-DCX guinea pig polyclonal antibody Millipore Ref AB2253 Living Colors® DsRed polyclonal antibody Takara/Clontech Ref 632496 Anti-GAPDH mouse monoclonal antibody Millipore Ref MAB374 Anti-GFP chicken polyclonal antibody Abcam Ref Ab13970 Anti-GPC4 rabbit polyclonal antibody Proteintech Ref 13048-1-AP Anti-GPR158 rabbit polyclonal antibody Sigma Ref SAB4502509 Anti-HA.11 mouse monoclonal antibody Biolegend Ref 901513 Anti-myc (clone 9E10) mouse monoclonal antibody Biolegend Ref 626802 Anti-PSD95 mouse monoclonal antibody Thermoscientific Ref MA1-045 Anti-Synaptotagmin7 mouse monoclonal antibody Millipore Ref MABN655 Anti-VGLUT3 mouse monoclonal antibody SySy Ref 135 211 Anti-Synaptoporin rabbit polyclonal antibody SySy Ref 102 002 Anti-synapsin1 rabbit polyclonal antibody SySy Ref 106 002 Anti-Tau (clone PC1C6) mouse monoclonal antibody Millipore Ref MAB3420 Anti-Vangl2 rabbit polyclonal antibody Montcouquiol et al., 2006 Ref 456 Anti-Znt3 mouse monoclonal antibody SySy Ref 197011 Anti-Rabbit Alexa 546 goat secondary antibody Invitrogen Ref A11035 Anti-Rabbit Alexa 488 goat secondary antibody Jackson Laboratory Ref 111-545-144 Anti-Mouse Alexa 594 goat secondary antibody Jackson Laboratory Ref 115-585-166 Anti-Guinea pig Alexa 488 goat secondary antibody Invitrogen Ref A11073 Anti-Chicken Alexa 488 goat secondary antibody Jackson Laboratory Ref 103-545-155 Anti-Rabbit HRP goat secondary antibody Jackson Laboratory Ref 111-035-144 Anti-Mouse HRP goat secondary antibody Jackson Laboratory Ref 115-035-146 Anti-Rabbit HRP mouse secondary antibody Jackson Laboratory Ref 211-032-171 In-situ hybridization probe RNAscope Probe-Mm-Vangl2 Advanced Cell Diagnostics Ref316781 Bacterial and virus strains AAV2/9-CaMKII(0.4)-mCherry- Vector Biolabs Service request [1. .. 9x1012 gcp/ml] AAV2/9-CaMKII(0.4)-mCherry-2A-mVANGL2 -WPRE Vector Biolabs Service request [5.9x1013 gcp/ml or 1.7x1013 gcp/ml] Experimental models: Organisms/strains Vangl2flox mice Prof. D. Henderson, UK Ramsbottom et al., 2014 Plos Genetics Emx1B6.129S2-Emx1tm1(cre)Krj/J (Emx1-Cre) mice Jackson Laboratory RRID:IMSR_JAX:005 628 Jo ur n l P re -p ro of Recombinant DNA GFP-Vangl2 Montcouquiol et al., 2006 HA-GPR158 Condomitti et al., 2018 HA-GPC4 Condomitti et al., 2018 GPC4-myc Origene Ref MR208834 Software and algorithms ImageJ NIH https://imagej.nih.gov/i j/; RRID: SCR_003070 Imaris BITPLANE http://www.bitplane.co m/imaris; RRID: SCR_007370 Microscope Image Browser (MIB) University of Helsinki http://mib.helsinki.fi/in dex.html Digital Micrograph Software Gatan http://www.gatan.com/ products/tem-analysis/ gatan-microscopysuite-software ZEN digital imaging for light microscopy Zeiss https://www.zeiss.com /microscopy/int/produc ts/ microscopesoftware/zen.html; RRID: SCR_013672 GraphPad Prism8 GraphPad Software https://www.graphpad. com/scientificsoftware/ prism/; RRID: SCR_002798 LasX Leica https://www.leicamicr osystems. com Ethovision XT 13 Noldus http://www.noldus.co m Neuromatic WaveMetrics Igor Pro 6.0 environment Image Lab software Viewpoint behavior Technology http://www.viewpoint. fr/en/home Other Digital Stereotaxic Frame, 18° Ear Bars WPI Ref 502300 Mouse/Neonatal Rat Adapter WPI Ref 502063 UMP III (one) & Micro4 Controller WPI Ref UMP3-1 Elevated 8-arm maze with automatized platform IMETRONIC https://www.imetronic. com/appareils/ Jo ur na l P re -p ro of ..

    Imaging:

    Article Title: The correct connectivity of the DG-CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Anti-bassoon mouse monoclonal antibody Enzo Life Sciences Ref ADI-VAM-PS003 Anti-DCX guinea pig polyclonal antibody Millipore Ref AB2253 Living Colors® DsRed polyclonal antibody Takara/Clontech Ref 632496 Anti-GAPDH mouse monoclonal antibody Millipore Ref MAB374 Anti-GFP chicken polyclonal antibody Abcam Ref Ab13970 Anti-GPC4 rabbit polyclonal antibody Proteintech Ref 13048-1-AP Anti-GPR158 rabbit polyclonal antibody Sigma Ref SAB4502509 Anti-HA.11 mouse monoclonal antibody Biolegend Ref 901513 Anti-myc (clone 9E10) mouse monoclonal antibody Biolegend Ref 626802 Anti-PSD95 mouse monoclonal antibody Thermoscientific Ref MA1-045 Anti-Synaptotagmin7 mouse monoclonal antibody Millipore Ref MABN655 Anti-VGLUT3 mouse monoclonal antibody SySy Ref 135 211 Anti-Synaptoporin rabbit polyclonal antibody SySy Ref 102 002 Anti-synapsin1 rabbit polyclonal antibody SySy Ref 106 002 Anti-Tau (clone PC1C6) mouse monoclonal antibody Millipore Ref MAB3420 Anti-Vangl2 rabbit polyclonal antibody Montcouquiol et al., 2006 Ref 456 Anti-Znt3 mouse monoclonal antibody SySy Ref 197011 Anti-Rabbit Alexa 546 goat secondary antibody Invitrogen Ref A11035 Anti-Rabbit Alexa 488 goat secondary antibody Jackson Laboratory Ref 111-545-144 Anti-Mouse Alexa 594 goat secondary antibody Jackson Laboratory Ref 115-585-166 Anti-Guinea pig Alexa 488 goat secondary antibody Invitrogen Ref A11073 Anti-Chicken Alexa 488 goat secondary antibody Jackson Laboratory Ref 103-545-155 Anti-Rabbit HRP goat secondary antibody Jackson Laboratory Ref 111-035-144 Anti-Mouse HRP goat secondary antibody Jackson Laboratory Ref 115-035-146 Anti-Rabbit HRP mouse secondary antibody Jackson Laboratory Ref 211-032-171 In-situ hybridization probe RNAscope Probe-Mm-Vangl2 Advanced Cell Diagnostics Ref316781 Bacterial and virus strains AAV2/9-CaMKII(0.4)-mCherry- Vector Biolabs Service request [1. .. 9x1012 gcp/ml] AAV2/9-CaMKII(0.4)-mCherry-2A-mVANGL2 -WPRE Vector Biolabs Service request [5.9x1013 gcp/ml or 1.7x1013 gcp/ml] Experimental models: Organisms/strains Vangl2flox mice Prof. D. Henderson, UK Ramsbottom et al., 2014 Plos Genetics Emx1B6.129S2-Emx1tm1(cre)Krj/J (Emx1-Cre) mice Jackson Laboratory RRID:IMSR_JAX:005 628 Jo ur n l P re -p ro of Recombinant DNA GFP-Vangl2 Montcouquiol et al., 2006 HA-GPR158 Condomitti et al., 2018 HA-GPC4 Condomitti et al., 2018 GPC4-myc Origene Ref MR208834 Software and algorithms ImageJ NIH https://imagej.nih.gov/i j/; RRID: SCR_003070 Imaris BITPLANE http://www.bitplane.co m/imaris; RRID: SCR_007370 Microscope Image Browser (MIB) University of Helsinki http://mib.helsinki.fi/in dex.html Digital Micrograph Software Gatan http://www.gatan.com/ products/tem-analysis/ gatan-microscopysuite-software ZEN digital imaging for light microscopy Zeiss https://www.zeiss.com /microscopy/int/produc ts/ microscopesoftware/zen.html; RRID: SCR_013672 GraphPad Prism8 GraphPad Software https://www.graphpad. com/scientificsoftware/ prism/; RRID: SCR_002798 LasX Leica https://www.leicamicr osystems. com Ethovision XT 13 Noldus http://www.noldus.co m Neuromatic WaveMetrics Igor Pro 6.0 environment Image Lab software Viewpoint behavior Technology http://www.viewpoint. fr/en/home Other Digital Stereotaxic Frame, 18° Ear Bars WPI Ref 502300 Mouse/Neonatal Rat Adapter WPI Ref 502063 UMP III (one) & Micro4 Controller WPI Ref UMP3-1 Elevated 8-arm maze with automatized platform IMETRONIC https://www.imetronic. com/appareils/ Jo ur na l P re -p ro of ..

    Light Microscopy:

    Article Title: The correct connectivity of the DG-CA3 circuits involved in declarative memory processes depends on Vangl2-dependent planar cell polarity signaling.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Antibodies Anti-bassoon mouse monoclonal antibody Enzo Life Sciences Ref ADI-VAM-PS003 Anti-DCX guinea pig polyclonal antibody Millipore Ref AB2253 Living Colors® DsRed polyclonal antibody Takara/Clontech Ref 632496 Anti-GAPDH mouse monoclonal antibody Millipore Ref MAB374 Anti-GFP chicken polyclonal antibody Abcam Ref Ab13970 Anti-GPC4 rabbit polyclonal antibody Proteintech Ref 13048-1-AP Anti-GPR158 rabbit polyclonal antibody Sigma Ref SAB4502509 Anti-HA.11 mouse monoclonal antibody Biolegend Ref 901513 Anti-myc (clone 9E10) mouse monoclonal antibody Biolegend Ref 626802 Anti-PSD95 mouse monoclonal antibody Thermoscientific Ref MA1-045 Anti-Synaptotagmin7 mouse monoclonal antibody Millipore Ref MABN655 Anti-VGLUT3 mouse monoclonal antibody SySy Ref 135 211 Anti-Synaptoporin rabbit polyclonal antibody SySy Ref 102 002 Anti-synapsin1 rabbit polyclonal antibody SySy Ref 106 002 Anti-Tau (clone PC1C6) mouse monoclonal antibody Millipore Ref MAB3420 Anti-Vangl2 rabbit polyclonal antibody Montcouquiol et al., 2006 Ref 456 Anti-Znt3 mouse monoclonal antibody SySy Ref 197011 Anti-Rabbit Alexa 546 goat secondary antibody Invitrogen Ref A11035 Anti-Rabbit Alexa 488 goat secondary antibody Jackson Laboratory Ref 111-545-144 Anti-Mouse Alexa 594 goat secondary antibody Jackson Laboratory Ref 115-585-166 Anti-Guinea pig Alexa 488 goat secondary antibody Invitrogen Ref A11073 Anti-Chicken Alexa 488 goat secondary antibody Jackson Laboratory Ref 103-545-155 Anti-Rabbit HRP goat secondary antibody Jackson Laboratory Ref 111-035-144 Anti-Mouse HRP goat secondary antibody Jackson Laboratory Ref 115-035-146 Anti-Rabbit HRP mouse secondary antibody Jackson Laboratory Ref 211-032-171 In-situ hybridization probe RNAscope Probe-Mm-Vangl2 Advanced Cell Diagnostics Ref316781 Bacterial and virus strains AAV2/9-CaMKII(0.4)-mCherry- Vector Biolabs Service request [1. .. 9x1012 gcp/ml] AAV2/9-CaMKII(0.4)-mCherry-2A-mVANGL2 -WPRE Vector Biolabs Service request [5.9x1013 gcp/ml or 1.7x1013 gcp/ml] Experimental models: Organisms/strains Vangl2flox mice Prof. D. Henderson, UK Ramsbottom et al., 2014 Plos Genetics Emx1B6.129S2-Emx1tm1(cre)Krj/J (Emx1-Cre) mice Jackson Laboratory RRID:IMSR_JAX:005 628 Jo ur n l P re -p ro of Recombinant DNA GFP-Vangl2 Montcouquiol et al., 2006 HA-GPR158 Condomitti et al., 2018 HA-GPC4 Condomitti et al., 2018 GPC4-myc Origene Ref MR208834 Software and algorithms ImageJ NIH https://imagej.nih.gov/i j/; RRID: SCR_003070 Imaris BITPLANE http://www.bitplane.co m/imaris; RRID: SCR_007370 Microscope Image Browser (MIB) University of Helsinki http://mib.helsinki.fi/in dex.html Digital Micrograph Software Gatan http://www.gatan.com/ products/tem-analysis/ gatan-microscopysuite-software ZEN digital imaging for light microscopy Zeiss https://www.zeiss.com /microscopy/int/produc ts/ microscopesoftware/zen.html; RRID: SCR_013672 GraphPad Prism8 GraphPad Software https://www.graphpad. com/scientificsoftware/ prism/; RRID: SCR_002798 LasX Leica https://www.leicamicr osystems. com Ethovision XT 13 Noldus http://www.noldus.co m Neuromatic WaveMetrics Igor Pro 6.0 environment Image Lab software Viewpoint behavior Technology http://www.viewpoint. fr/en/home Other Digital Stereotaxic Frame, 18° Ear Bars WPI Ref 502300 Mouse/Neonatal Rat Adapter WPI Ref 502063 UMP III (one) & Micro4 Controller WPI Ref UMP3-1 Elevated 8-arm maze with automatized platform IMETRONIC https://www.imetronic. com/appareils/ Jo ur na l P re -p ro of ..

    Plasmid Preparation:

    Article Title: Mitotic ER-mitochondria contact enhances mitochondrial Ca 2+ influx to promote cell division.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER BSA Servicebio G5001 STLC Sigma-Aldrich SPE006 MG132 Sigma-Aldrich M8699 Bleomycin sulfate MedChemExpress HY-17565 Protease Inhibitor Cocktail MedChemExpress HY-K0010 Thymidine Sigma-Aldrich V900391 Enhanced chemiluminescence Sigma-Aldrich WBKLS0500 ATP MedChemExpress HY-B0345A DTT Sigma-Aldich D0632 Histamine 3A Chemicals A02646 Triton X-100 Sigma-Aldrich T9284 CGP37157 MedChemExpress HY-15754 EMbed 812 resin Electron Microscopy Sciences #14120 1.4-nm gold-conjugated Fab’ fragment Nanoprobes #2004 Critical commercial assays FastStart Essential DNA Green Master Roche 06402712001 Duolink PLA assay kit Sigma-Aldrich DUO92008 JC-1 assay kit MedChemExpress HY-K0601 Seahorse XF Cell Mito Stress Test Kit Agilent 103015–100 GoldEnhance EM Plus kit Nanoprobes #2114 Deposited data mass spectrometry data of MAM This paper IProX: IPX0006293000 mass spectrometry data of GFP-LBR coIP This paper IProX: IPX0006297000 Experimental models: Cell lines HEK293T cell ATCC CRL-11268 HeLa cell ATCC CCL-2 HCT116 cell ATCC CCL-247 LBR KO HeLa cell This paper N/A EMD KO HeLa cell This paper N/A Oligonucleotides LBR KO sgRNA1: 50- TGACCTTGATCGACTCCCT-30 This paper N/A LBR KO sgRNA2: 50- TTCCCCTTCCAGACGCCGA-30 This paper N/A EMD KO sgRNA: 50- GCGCAGCAAGG TGGTCAGCT-30 This paper N/A Recombinant DNA Plasmid: 4mt-GCaMP6 Gift from Dr. D. De Stefani, University of Padua, Italy N/A Plasmid: mito-R-GECO1.2 Gift from Drs. Jianguo Chen and Junlin Teng, Peking University, China N/A Plasmid: pEGFP-N1-LBR This paper N/A Plasmid: pEGFP-C2-Sec61b This paper N/A Plasmid: pEGFP-N1-LBR211–615 This paper N/A Plasmid: pEGFP-N1-LBR1–585 This paper N/A Plasmid: pEGFP-N1-LBRD211–585 This paper N/A Plasmid: pEGFP-N1-LBR1–210 This paper N/A Plasmid: pEGFP-N1-LBR211–585 This paper N/A (Continued on next page) Cell Reports 43, 114794, October 22, 2024 17 .. REAGENT or RESOURCE SOURCE IDENTIFIER Plasmid: pEGFP-N1-LBR5A This paper N/A Plasmid: pEGFP-N1-LBR5D This paper N/A Plasmid: pcDNA3.1-flag- AKAP1-BFPUBC6 This paper N/A Plasmid: pcDNA3.1-mCherry-COX8 This paper N/A Plasmid: RFP-H2B Our Laboratory N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij/ Volocity v.6.1.1 PerkinElmer N/A Imaris v.9.3.1 Bitplane https://imaris.oxinst.com/versions/9-3 Amira 2019.2.0 Thermo Scientific https://www.thermofisher.cn/cn/zh/home/ global/forms/industrial/amira-softwaretrial. html GraphPad Prism v.8.2.1 GraphPad https://www.graphpad.com/ Seahorse Analytics Agilent https://www.agilent.com.cn/zh-cn/ product/cell-analysis/real-time-cellmetabolic-analysis/xf-software/agilentseahorse-analytics-787485 LightCycler Software Version1.1.0 Roche N/A .. HCT116, HEK-293T and HeLa cells were purchased from ATCC.

    Article Title: ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER NuPAGE TM LDS Sample Buffer (4X) Thermo Fisher Scientific Cat# NP0008 DTT Sigma Cat# D9779 Dynabeads Protein A Thermo Fisher Scientific Cat# 10008D Dynabeads Protein G Thermo Fisher Scientific Cat# 10009D NP-40 Sigma Cat# I8896 Tris-HCl (1M, pH 8.0) Thermo Fisher Scientific Cat# AM9856 Tris-HCl (1M, pH 7.0) Thermo Fisher Scientific Cat# AM9850 Glycerol Sigma Cat# G5516 Protease inhibitor (cOmplete EDTA-free) Roche Cat# 11873580001 Tween 20 Fisher Cat# BP337-500 Pierce Universal Nuclease Thermo Fisher Scientific Cat# 88701 Glucose Sigma Cat# G7021 Oligomycin-A Sigma Cat# 75351 2DG AlfaAesar Cat# AAL0733806 FCCP Sigma Cat# C2920 Rotenone Sigma Cat# 557368 1M MgCl 2 Thermo Fisher Scientific Cat# AM9530G 0.5M EDTA (pH 8.0) Sigma Cat# 324506 Sodium deoxycholate Sigma Cat# D6750 SDS Sigma Cat# L3771 RNasin® Plus Promega Cat# N2615 GlycoBlue TM Thermo Fisher Scientific Cat# AM9516 ERCC RNA Spike-In Mix Thermo Fisher Scientific Cat# 4456740 Critical commercial assays NEBNext® Ultra TM II Directional RNA Library Prep Kit for Illumina® NEB Cat# E7765 RiboMinus TM Eukaryote Kit for RNA-seq Thermo Fisher Scientific Cat# A1083708 Direct-zol RNA Miniprep kit Zymo Research Cat# R2052 Deposited data Raw and analyzed sequencing data This paper GSE293278 Proteomics data This paper PXD069896 Experimental models: Cell lines WT-HEK-293T Chung et al. 14 N/A ADAR1 KO-HEK-293T Chung et al. 14 N/A WT-HUES8 Chung et al. 14 N/A ADAR1 KO-HUES8 Chung et al. 14 N/A WT-HeLa Pfaller et al. 16 N/A ADAR1p150KO-HeLa Pfaller et al. 16 N/A ADAR1 KO-HeLa Pfaller et al. 16 N/A WT-HAP1 This paper N/A E912A KI-HAP1 This paper N/A ADAR1 KO-HAP1 This paper N/A Human Dermal Fibroblasts ATCC Cat# PCS-201-012 Oligonucleotides Primers for qRT-PCR, see Table S9 This paper N/A gRNA_ADAR1 KO_clone #1_1: CATGAGATGTGACTGCACAG This paper N/A (Continued on next page) Cell Reports 45, 117026, March 24, 2026 23 .. REAGENT or RESOURCE SOURCE IDENTIFIER gRNA_ADAR1 KO_clone #1_2: GGAATCCATGATGCCCAACA This paper N/A gRNA_ADAR1 KO_clone #2_1: TTCTTGTAGGGTGAACACCG This paper N/A gRNA_ADAR1 KO_clone #2_2: TGATTGGTTTTGGCCGTACG This paper N/A gRNA_E912A KI: GCCATGCAGAAATAATCTCC This paper N/A Donor template_E912A KI_clone #1: AAGGAGATTCTCTCAGCCTAAA AGGAGAAACTGTCAATGACTGCCA TGCAGCCATAATCTCCCGGAGAGGC TTCATCAGGTGAGCGAGGTCAGAGCTG TGGCCCGGCTGCCCGG This paper N/A Donor template_E912A KI_clone #2: TCTCAGCCTAAAAGGAGAAACTGTCAA TGACTGCCATGCAGCCATAATC TCCAGAAGAGGCTTCATCAGG TGAGCGAGGTCAGAGCTGTGG CCCGGCTGCCCGG This paper N/A ON-TARGETplus TM siRNA targeting ADAR1 Dharmacon Cat# L-008630-00-0005 ON-TARGETplus TM siRNA targeting PNPT1 Dharmacon Cat# L-019454-01-0005 ON-TARGETplus TM siRNA targeting SUV3 Dharmacon Cat# L-017841-01-0005 Recombinant DNA pSpCas9(BB)-2A-GFP (PX458) Ran et al. 95 Addgene plasmid Cat# 48138 pcDNA TM 3.1 Thermo Fisher Scientific Cat# V79020 ADAR1p110_pcDNA TM 3.1 This paper N/A ADAR1p150_pcDNA TM 3.1 This paper N/A p150_EAA_pcDNA TM 3.1 This paper N/A p150_E912A_pcDNA TM 3.1 This paper N/A p150_EAA/E912A_pcDNA TM 3.1 This paper N/A hPTGS2_pcDNA3.1 Chen et al. 96 Addgene plasmid Cat# 102498 ISG15_pcDNA TM 3.1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij Imaris Oxford Instruments https://imaris.oxinst.com Prism 10.0 GraphPad Software https://www.graphpad.com/features DIA-NN APTILA https://aptila.bio NormalizerDE Willforss et al. 97 https://normalyzerde.immunoprot.lth.se FastQC v0.11.5 Andrews et al. 98 http://www.bioinformatics.babraham.ac. uk/projects/fastqc Fastp v0.20.1 Chen et al. 99 https://github.com/OpenGene/fastp STAR v2.7.3a and v2.7.9a Dobin et al. 100 https://github.com/alexdobin/STAR featureCounts v1.6.4 Liao et al. 101 https://subread.sourceforge.net/ featureCounts.html DESeq2 Love et al. 67 https://github.com/thelovelab/DESeq2 RepeatMasker Smit et al. 102 https://www.repeatmasker.org BEDTools v2.30.0 Quinlan et al. 103 https://bedtools.readthedocs.io/en/latest Cutadapt v4.9 Martin et al. 104 https://cutadapt.readthedocs.io/en/stable SEISMIC-RNA v2.7.9a Allan et al. 52 https://github.com/rouskinlab/seismic-rna BWA 0.7.18-r1243-dirty Li et al. 105 https://github.com/lh3/bwa DaPars v2.1 Li et al. 56 https://github.com/3UTR/DaPars2 24 Cell Reports 45, 117026, March 24, 2026 ..

    Data-independent acquisition:

    Article Title: ADAR1 regulates dsRNA formation in nuclear and mitochondrial transcripts through editing-dependent and -independent mechanisms.
    Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER NuPAGE TM LDS Sample Buffer (4X) Thermo Fisher Scientific Cat# NP0008 DTT Sigma Cat# D9779 Dynabeads Protein A Thermo Fisher Scientific Cat# 10008D Dynabeads Protein G Thermo Fisher Scientific Cat# 10009D NP-40 Sigma Cat# I8896 Tris-HCl (1M, pH 8.0) Thermo Fisher Scientific Cat# AM9856 Tris-HCl (1M, pH 7.0) Thermo Fisher Scientific Cat# AM9850 Glycerol Sigma Cat# G5516 Protease inhibitor (cOmplete EDTA-free) Roche Cat# 11873580001 Tween 20 Fisher Cat# BP337-500 Pierce Universal Nuclease Thermo Fisher Scientific Cat# 88701 Glucose Sigma Cat# G7021 Oligomycin-A Sigma Cat# 75351 2DG AlfaAesar Cat# AAL0733806 FCCP Sigma Cat# C2920 Rotenone Sigma Cat# 557368 1M MgCl 2 Thermo Fisher Scientific Cat# AM9530G 0.5M EDTA (pH 8.0) Sigma Cat# 324506 Sodium deoxycholate Sigma Cat# D6750 SDS Sigma Cat# L3771 RNasin® Plus Promega Cat# N2615 GlycoBlue TM Thermo Fisher Scientific Cat# AM9516 ERCC RNA Spike-In Mix Thermo Fisher Scientific Cat# 4456740 Critical commercial assays NEBNext® Ultra TM II Directional RNA Library Prep Kit for Illumina® NEB Cat# E7765 RiboMinus TM Eukaryote Kit for RNA-seq Thermo Fisher Scientific Cat# A1083708 Direct-zol RNA Miniprep kit Zymo Research Cat# R2052 Deposited data Raw and analyzed sequencing data This paper GSE293278 Proteomics data This paper PXD069896 Experimental models: Cell lines WT-HEK-293T Chung et al. 14 N/A ADAR1 KO-HEK-293T Chung et al. 14 N/A WT-HUES8 Chung et al. 14 N/A ADAR1 KO-HUES8 Chung et al. 14 N/A WT-HeLa Pfaller et al. 16 N/A ADAR1p150KO-HeLa Pfaller et al. 16 N/A ADAR1 KO-HeLa Pfaller et al. 16 N/A WT-HAP1 This paper N/A E912A KI-HAP1 This paper N/A ADAR1 KO-HAP1 This paper N/A Human Dermal Fibroblasts ATCC Cat# PCS-201-012 Oligonucleotides Primers for qRT-PCR, see Table S9 This paper N/A gRNA_ADAR1 KO_clone #1_1: CATGAGATGTGACTGCACAG This paper N/A (Continued on next page) Cell Reports 45, 117026, March 24, 2026 23 .. REAGENT or RESOURCE SOURCE IDENTIFIER gRNA_ADAR1 KO_clone #1_2: GGAATCCATGATGCCCAACA This paper N/A gRNA_ADAR1 KO_clone #2_1: TTCTTGTAGGGTGAACACCG This paper N/A gRNA_ADAR1 KO_clone #2_2: TGATTGGTTTTGGCCGTACG This paper N/A gRNA_E912A KI: GCCATGCAGAAATAATCTCC This paper N/A Donor template_E912A KI_clone #1: AAGGAGATTCTCTCAGCCTAAA AGGAGAAACTGTCAATGACTGCCA TGCAGCCATAATCTCCCGGAGAGGC TTCATCAGGTGAGCGAGGTCAGAGCTG TGGCCCGGCTGCCCGG This paper N/A Donor template_E912A KI_clone #2: TCTCAGCCTAAAAGGAGAAACTGTCAA TGACTGCCATGCAGCCATAATC TCCAGAAGAGGCTTCATCAGG TGAGCGAGGTCAGAGCTGTGG CCCGGCTGCCCGG This paper N/A ON-TARGETplus TM siRNA targeting ADAR1 Dharmacon Cat# L-008630-00-0005 ON-TARGETplus TM siRNA targeting PNPT1 Dharmacon Cat# L-019454-01-0005 ON-TARGETplus TM siRNA targeting SUV3 Dharmacon Cat# L-017841-01-0005 Recombinant DNA pSpCas9(BB)-2A-GFP (PX458) Ran et al. 95 Addgene plasmid Cat# 48138 pcDNA TM 3.1 Thermo Fisher Scientific Cat# V79020 ADAR1p110_pcDNA TM 3.1 This paper N/A ADAR1p150_pcDNA TM 3.1 This paper N/A p150_EAA_pcDNA TM 3.1 This paper N/A p150_E912A_pcDNA TM 3.1 This paper N/A p150_EAA/E912A_pcDNA TM 3.1 This paper N/A hPTGS2_pcDNA3.1 Chen et al. 96 Addgene plasmid Cat# 102498 ISG15_pcDNA TM 3.1 This paper N/A Software and algorithms ImageJ NIH https://imagej.nih.gov/ij Imaris Oxford Instruments https://imaris.oxinst.com Prism 10.0 GraphPad Software https://www.graphpad.com/features DIA-NN APTILA https://aptila.bio NormalizerDE Willforss et al. 97 https://normalyzerde.immunoprot.lth.se FastQC v0.11.5 Andrews et al. 98 http://www.bioinformatics.babraham.ac. uk/projects/fastqc Fastp v0.20.1 Chen et al. 99 https://github.com/OpenGene/fastp STAR v2.7.3a and v2.7.9a Dobin et al. 100 https://github.com/alexdobin/STAR featureCounts v1.6.4 Liao et al. 101 https://subread.sourceforge.net/ featureCounts.html DESeq2 Love et al. 67 https://github.com/thelovelab/DESeq2 RepeatMasker Smit et al. 102 https://www.repeatmasker.org BEDTools v2.30.0 Quinlan et al. 103 https://bedtools.readthedocs.io/en/latest Cutadapt v4.9 Martin et al. 104 https://cutadapt.readthedocs.io/en/stable SEISMIC-RNA v2.7.9a Allan et al. 52 https://github.com/rouskinlab/seismic-rna BWA 0.7.18-r1243-dirty Li et al. 105 https://github.com/lh3/bwa DaPars v2.1 Li et al. 56 https://github.com/3UTR/DaPars2 24 Cell Reports 45, 117026, March 24, 2026 ..



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